Endocrine Abstracts

Introduction: The anabolic hormones, namely GH, testosterone and dehydroepiandrosterone, as well as the reproductive function of women, enter a period of progressive insufficiency which is characteristically designated as somatopause, andropause and adrenopause respectively. The aim of the study was to compare the endocrine functions between premenopausal and postmenopausal women.Subjects and methods: The study was included 40 premenopausal (mean age 34....

Introduction: Thyroid and parathyroid pathology may coexist; classically, this is described in multiple endocrine neoplasia. Other nonsyndromic scenarios result in pathologies of these endocrine organs coexisting. The aim of the investigation the chracteristics of thyroid pathology in patients with parathyroid adenoma.Subjects and method: The study population included 42 (26 patients age <60 years vs 16 patients age ≥60 years) patients with par...

Incidentalomas (AI) are clinically inapparent adrenal masses. Patients present hormone excess or mass effect, but part of them is clinically silent. They are discovered inadvertently in the course of diagnostic testing or treatment for other clinical conditions. The aim of the study was to investigate the clinical value of tumor size and hormonal status of elderly patients with adrenal incidentaloma (AI).Subjects and Methods: Forty-four elderly with AI w...

Introduction: Hurthle cell of adenoma (HCA)of thyroid gland is rare neoplasms of the thyroid. They have been found in association with various benign thyroid conditions like Hashimoto’s thyroiditis, hyperthyroidism, nodular goiter, and thyroid neoplasms; where they often represent oncocytic metaplasia. Oncocytic cells are also present in normal parathyroid tissue. Oncocytic parathyroid adenomas, predominantly (more than 70%) or exclusively composed of oncocytic cells are ...

Introduction: Hyperthyroidism in the elderly can present with subtle nonspecific complaints. Patients with long-standing goiter can develop autonomous nodules resulting in toxic nodular goiter.Case report: An 86 year old women was referred from gastroenterologist for thyroid disease because of low TSH. She had diarrhea with five to eight bowel movements a day for six months. She denied palpitations, heat intolerance or muscle weakness. She had been noted...

Introduction: Low serum levels of 25-hydroxyvitamin D (25(OH)D3) lower than has been reported to be prevalent in several autoimmune diseases. The aims of the study were i) to evaluate the 25(OH)D3 levels in patients with Hashimato’s thyroiditis (HT) and ii) to investigate the relationships between 25(OH)D3, TSH, free T4, free T3, and anti-thyroid peroxidase (anti-TPO) levels in elderly patients with HT.Subjects and method: Stud...

Objective: The aim of our study was to investigate the relationships between insulin receptor substrat-1 (IRS-1) and insulin receptor substrat-2 (IRS-2) gene polymorphisms and cardiovascular factors such as blood pressures, BMI, LDL- cholesterol, triglyceride, HOMA-IR, homocysteine, hsCRP and fibrinogen levels in patients with metabolic syndrome (MetS).Subjects and methods: The study population included 100 patients with MetS and 30 patients without MetS...

Introduction: Biochemical and clinical vitamin B12 deficiency has been demonstrated to be highly prevalent among patients with diabetes mellitus. The aims of the study were 1. to compare the vitamin B12 (VB12) levels, and 2. to investigate the relationship between VB12, fasting insulin and HOMA-IR levels in elderly patients with metabolic syndrome (MetS).Subjects and method: Study population included 121 (mean age 64.3±14.1 years) (80 female, 41 mal...

The aims of the study were to determine the frequency of falls in elderly patients with type 2 diabetes mellitus and to evaluate the risk factors for falls. In the study, 100 (mean age 64.9±11.0 years) (65 females, 35 males) elderly patients with type 2 DM were enrolled. Medical record abstraction of sociodemographic, clinical, and laboratory data was performed retrospectively. Medication characteristics, comorbidities, location and height of fall, associated injuries and...

Aims: The metabolic syndrome (MetS) is a summary measure of important CVD risk factors that frequently coexist. The syndrome is evident in 20–30% of middle-aged women and has been linked to the development of CVD and diabetes. The aim of the study was to examine the differences in demographic and clinical profiles among older (≥60 years) and younger (<60 years) patients with MetS.Methods: The study was included 45 older (mean age 63.1&#177...